
Only seen four of these on a somewhat regular basis at any time: Scrubs, South Park, Arrested Development when it first aired, and some of what was syndicated of Red Dwarf on PBS when I was younger. I should really watch Louie, I like his stand up.
Out of those, South Park is my favorite. Love how topical and irreverent the show is, and how it gives valid moral lessons in the midst of its vulgarity.